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Search Results to Stephanie Byrum

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One or more keywords matched the following properties of Byrum, Stephanie

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overview My research focus involves a translational approach for the identification of cancer systems biology, from the bench to the bedside. I have performed experiments ranging from collecting patient samples, to performing proteomic and genomic analyses, using bioinformatics to mine large complex data sets, and identify important clinical markers for metastatic breast cancer and melanoma. I have formal training in bioinformatics and mass spectrometry. My bioinformatics skill set includes: proteomics (label-free, stable isotope tags, SILAC, TMT-labeling, intensity-based analysis), epigenetics (quantitation of histone posttranslational modifications and chromatin remodelers), genomics (microarray, ChIP-seq, RNA-seq), metagenomics, biostatistics and data mining, and pathway and functional analysis. My research is currently focused on developing multi-omics data integration and proteogenomics applications.

One or more keywords matched the following items that are connected to Byrum, Stephanie

Item TypeName
Academic Article Proteomic analysis of bone cancer: a review of current and future developments.
Academic Article Identification of PTHrP(12-48) as a plasma biomarker associated with breast cancer bone metastasis.
Academic Article The promise of bone cancer proteomics.
Academic Article A quantitative proteomic analysis of FFPE melanoma.
Concept Breast Neoplasms
Concept Bone Neoplasms
Concept Brain Neoplasms
Concept Colonic Neoplasms
Concept Liver Neoplasms
Concept Colorectal Neoplasms
Concept Prostatic Neoplasms
Concept Gastrointestinal Neoplasms
Concept Lung Neoplasms
Concept Epigenomics
Concept Skin Neoplasms
Concept Neoplasms, Experimental
Concept Early Detection of Cancer
Concept Neoplasms
Academic Article Bone Cancer: Progression and Therapeutic Approaches
Academic Article TBX2 blocks myogenesis and promotes proliferation in rhabdomyosarcoma cells.
Academic Article A CRISPR-based approach for proteomic analysis of a single genomic locus.
Academic Article ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.
Academic Article Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma.
Academic Article Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma.
Grant Development of technology for high resolution epigenetic profiling of chromatin
Grant Technology for Identification of Epiproteomes in Tissue Samples
Grant G-quadruplex DNA as a chemical signaling agent
Grant Identification of combinatorial histone post-translational modifications within t
Grant Functions and Mechanisms of Helicases and G-Quadruplex Nucleic Acids
Academic Article Proteomic characterization of the arsenic response locus in S. cerevisiae.
Grant Epigenetic profiling and enzymatic regulation of H3K23me3 during cellular differentiation - Continuation - Continuation - Continuation
Grant Epigenetic modulation of CD4+ T cell differentiation and autoimmunity by trichloroethylene
Academic Article Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression.
Academic Article Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion.
Academic Article Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma.
Academic Article Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity.
Academic Article Multi-omics data integration considerations and study design for biological systems and disease.
Academic Article Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer.
Academic Article Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells.
Academic Article Phase separation drives aberrant chromatin looping and cancer development.
Academic Article Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer.
Academic Article Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy.
Academic Article A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells.
Academic Article Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy.
Academic Article Circulating Exosomal microRNAs as Predictive Biomarkers of Neoadjuvant Chemotherapy Response in Breast Cancer.
Academic Article Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic.
Academic Article Proteomic profiling of tear fluid as a promising non-invasive screening test for colon cancer.
Academic Article Discovery of the inhibitor of DNA binding 1 as a novel marker for radioresistance in pancreatic cancer using genome-wide RNA-seq.
Academic Article Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy.
Academic Article Expression of integrin ?-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics.
Academic Article Neoplastic signatures: Comparative proteomics of canine hepatobiliary neuroendocrine tumors to normal niche tissue.
Academic Article Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells.
Academic Article Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma.
Academic Article Evaluation of traditional targeted axillary dissection eligibility criteria for node-positive breast cancer after neoadjuvant chemotherapy in a prospective multicenter registry.

Search Criteria
  • Cancer
  • Epigenetics